CONVERIS Research database: EU Projects

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PIDNET - A Chinese Network for Primary Immunodeficiency
We have previously created a network for colleagues working on the genetics of primary immunodeficiency diseases (PID) and their treatment within the EU. This project is one of the finalists for the Descartes Prize in 2005. We extended this work to encompass the NAS countries in 2001, again within ...

ALLOMICROVAC - A combined microbicidal-immunizing strategy against SIV and HIV infection
The objective of the proposed project is to establish proof of concept that a tri-molecular construct, consisting of MHC antigens combined with microbial HSP70 and extracellular CCR5 can be utilized in microbicidal, preventive and therapeutic immunisation. This strategy utilizes a novel ...

EUROHEAR - Advances in hearing science : from functional genomics to therapies
EuroHear has two closely inter-related objectives.These are (1 )to provide fundamental knowledge about the development and function of the inner ear,and (2) to identify the molecular defects underlying hereditary hearing impairments (HI), including presbycusis,one of the most frequent forms of ...

EMBRACE - A European Model for Bioinformatics Research and Community Education
The objective of this network is to draw together a wide group of experts throughout Europe who are involved in the use of information technology in the biomolecular sciences. The EMBRACE network will optimise informatics and information exploitation by pure and applied biological scientists in ...

PROCARDIS - A genome-wide mapping and functional genomics approach to elucidating PRecOcious Coronary ARtery DISease
A programme is proposed, by an established European consortium, that will exploit advances in complex trait genetics and functional genomics to discover novel susceptibility genes for coronary artery disease (CAD). The aim is to identify novel proteins and pathways implicated in atherosclerosis and ...

AVIP - AIDS VACCINE INTEGRATED PROJECT
Vaccines based on viral structural products (Env/Gag/Pol) alone have failed to prevent infection by HIV/SIV. Vaccines based on viral regulatory gene products (Tat/Rev/Nef) have contained virus replication preventing disease onset. A vaccine combining both (combined vaccine) is likely to be superior ...

MYOAMP - Amplification of human myogenic stem cells in clinical conditions
The aim of this network is to synergize expertises from European basic researchers, leaders in their field, and European SMEs specialized in stem cell amplification and in safety of these procedures, to set up conditions for autologous transfer of human stem cells in GMP conditions for the ...

GABRIEL - A multidisciplinary study to identify the genetic and environmental causes of asthma in the European Community
GABRIEL provides an integrated multidisciplinary program of post-genome research. Internationally leading groups will apply knowledge of epidemiology, genetics, genomics, proteomics, bioinformatics, statistics, environmental ecology and immunology into the causes of asthma in the European ...

GENECURE - Applied GENomic StratEgies for Treatment and Prevention of Cardiovascular death in Uraemia and End stage REnal Disease
In renal failure cardiovascular risk (CV) is greatly enhanced, posing a large burden on both patient and society. The development of CV disease in renal patients partly corresponds to that in non-renal populations, but factors specific to renal failure are crucially involved as well. Elucidation of ...

EURAPS - Autoimmune polyendocrine syndrome type I - a rare disorder of childhood as a model for autoimmunity
Autoimmune polyendocrine syndrome type I (APS I), a rare genetic disorder of childhood, has proven to be an invaluable tool in understanding autoimmune reactions. APS I (OMIM 240300), also known as APECED (autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy), is a severe autosomal ...

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